Overview of hepatitis C infection, molecular biology, and new treatment
نویسندگان
چکیده
منابع مشابه
Molecular biology of hepatitis C infection.
Hepatitis C infection (HCV) is an emerging epidemic. Liver specialists are managing this disease with limited scientific information about the underlying pathogenesis and treatment. The current review offers a molecular dissection of infection, a snapshot of the HCV life cycle, and emerging strategies for antiviral therapy.
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Interferon (IFN) is a protein that occurs naturally in the body in very small amounts. It assists the immune system in fighting, for example, certain cancers and viruses by ‘interfering’ with and inhibiting the development and replication of cells. In the 1970s, medical science developed a synthetic IFN. Interferon therapy became standard treatment for hepatitis C infection following the identi...
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Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for the patients with HCV-related liver disease has advanced considerably thanks to an enhanced understanding of the pathophysiology of the disease, and because of developments in diagnostic procedures and improvements in therapy an...
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Interferon (IFN)-based therapy, the cornerstone for treatment of hepatitis C virus (HCV) infection, is generally considered to be the single most effective treatment strategy for this infection. Although most adverse effects of IFN therapy respond very well to the cessation of this drug, there are reports of serious irreversible adverse effects. This review article evaluates the adverse effects...
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교신저자: 정우진, 700-712, 대구시 중구 달성로 56, 계명대학교 의과대학 내과학교실 Correspondence to: Woo Jin Chung, Department of Internal Medicine, School of Medicine Keimyung University, 56 Dalsung-ro, Jung-gu, Daegu 700-712, Korea. Tel: +82-53-250-7088, Fax: +82-53-250-7442, E-mail: [email protected] Financial support: None. Conflict of interest: None. 요약: 페그인터페론의 등장 이후로 만성 C형간염의 치료 성적은 유의하게 개선되어 왔지만 치료시 동반되는 부작용과 일부 유전...
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ژورنال
عنوان ژورنال: Journal of Infection and Public Health
سال: 2020
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2019.11.015